Metabolic Regulation of Cell Differentiation

Mini Review of cell differentiation including some of my own findings.

Abstract: 

Growing research suggests that metabolism itself may play a role in inducing cellular differentiation. This concept stems from three different experimental approaches involving hypoxia, nutrient metabolites, and phosphate analogues, that appear to modulate cellular differentiation by influencing the available cellular energy needed for biosynthetic processes. Possible explanatory mechanisms that could lead to subsequent changes in gene expression include the availability of key metabolites needed for epigenetic changes to occur and/or kinases that can sense the cellular energy charge.

This publication has been peer reviewed.
Publication Type: 
Journal Article
Authors: 
Elizabeth Frayne, PhD
Year of Publication: 
2020
Journal, Book, Magazine or Other Publication Title: 
Advanced Chemicobiology Research
Volume: 
Vol 1
Issue: 
1
Pages: 
1-4
Publisher: 
Universal Wiser
Date Published: 
Wednesday, November 11, 2020
Place Published: 
Online
Publication Language: 
English
DOI: 
open access
Editors: 
Majid Monajjemi
Boyer's Domain: 

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